Inositol is a polyol that exists in nine different stereoisomers, among which Myo-inositol and D-chiro-inositol are the most biologically relevant. Both act as second messengers of insulin, regulating different insulin-dependent processes and each contributing specifically to proper glucose metabolism. Furthermore, Myo-inositol also functions as a second messenger for follicle-stimulating hormone (FSH), which regulates follicular growth up to ovulation.
Manganese is a micronutrient that acts as a cofactor for many metalloenzymes and proteins involved in cellular metabolism and in major oxidative stress response pathways. Manganese is essential for obtaining the intracellular active form of D-chiro-inositol.
Folic Acid is a water-soluble B vitamin. It contributes to normal amino acid metabolism and plays a role in the process of cell division. It supports maternal tissue growth during pregnancy and contributes to normal homocysteine metabolism.
Vitamin D is a fat-soluble vitamin synthesized by the body upon exposure to sunlight. It helps maintain normal bones and is involved in the process of cell division. Vitamin D is an essential hormone in regulating the calcium/phosphorus balance and plays a role in the pathogenesis of inflammation, insulin resistance and obesity.