Inositol is a polyol that exists in nine different stereoisomeric forms, among which myo-inositol and D-chiro-inositol are the most biologically relevant. Both act as insulin second messengers, regulating different insulin-dependent processes and contributing, each in a specific way, to proper glucose metabolism. In addition, myo-inositol also acts as a second messenger for follicle-stimulating hormone (FSH), which regulates follicular growth up to ovulation.
Manganese is a micronutrient that serves as a cofactor for numerous metalloenzymes and proteins involved in cellular metabolism and the body's main oxidative stress response pathways. Manganese is essential for the formation of the intracellular active form of D-chiro-inositol.
Folic Acid is a water-soluble B-group vitamin. It contributes to the normal metabolism of amino acids and plays a role in the process of cell division. It also supports maternal tissue growth during pregnancy and contributes to normal homocysteine metabolism.
Vitamin D is a fat-soluble vitamin that is synthesized by the body following exposure to sunlight. It contributes to the maintenance of normal bones and plays a role in the process of cell division. Vitamin D is an essential hormone involved in the regulation of calcium and phosphorus homeostasis, as well as in the pathogenesis of inflammation, insulin resistance, and obesity.